A brother-in-law has been in the printing business for decades now (yes, seriously), but somehow his business seems to have stagnated. I think one of the main reasons is that he is a bit afraid to invest on other ways of printing, specially when it comes to buying expensive equipments. Being cautious is fine, but at this age and time, going digital and being aggressive with his printing methods could be vital. For starters, he may want to check out printdirectforless business card printing. I know that they used to print business cards a while back, when he and his brothers lived together.
Of course, where his business goes is entirely his decision. I just wish that it will prosper once again, like it did when he first handled it.... :)